Prevalence of group B streptococcus colonisation and pregnancy outcomes of pregnant women at Hanoi Obstetrics and Gynecology Hospital

Abstract

Objectives: To determine the prevalence of maternal group B streptococcus (GBS) colonisation and pregnancy results of pregnant women at Hanoi Obstetrics and Gynecology Hospital. Materials and methods: Retrospective descriptive with 537 pregnant women delivered at the Hanoi Obstetrics and Gynecology Hospital in 2021, GBS was detected based on culture, isolation, and identification of bacteria from the vaginarectum samples at 36-37+6 weeks gestation. Results: The prevalence of maternal GBS colonisation was 18.1%. 87.5% of GBS colonisations were applied to intrapartum
antibiotic prophylaxis during labour or ruptured membranes. Diabetes increased the risk of carrying GBS (OR=2.3, 95%CI: 1.17-4.34). Maternal GBS colonisation increased the risk of rupture of membranes (OR 3.09, 95%CI: 1.95-4.85) and antibiotic treatment of newborns (OR=3.39, 95%CI: 1.05-10.92). However, there was no increased risk for cesarean section or postpartum infection (p>0.05). Maternal GBS colonisation with intrapartum antibiotic prophylaxis has not increased the risk for early neonatal (OR=0.55, 95%CI: 0.06-5.44). Conclusion: The prevalence of maternal GBS colonisation was 18.1%. Pregnant women carrying GBS treated with intrapartum antibiotic prophylaxis did not increase the risk of maternal adverse pregnancy outcomes and early neonatal infection.