Research of antibiotics resistance of gram-negative bacteria strains causing urinary tract infections isolated at Nghe An Friendship General Hospital

Abstract

Urinary tract infection is one of the common infections, which can recur many times if not diagnosed early and treated effectively. Gram-negative bacteria are the most common pathogens. In this study, the author determined the pathogenic gram-negative bacteria and their level of antibiotic resistance with the aim of making the treatment effective, reducing the cost of treatment, and limiting the proliferation of antibiotic-resistant bacteria. A descriptive cross-sectional study on 400 strains of gram-negative bacteria showed that the most common bacteria were Escherichia coli 38.48%, Pseudomonas aeruginosa 14.15%, Klebsiella pneumoniae 13.32%. E. coliis resistant to Cephalosporine, Quinolone antibiotics from 65.0-74.8%, Carbapenem 6.8-8.6%, producing extended-spectrum beta-lactamase (ESBL) 58.4%. K. pneumoniae is resistant to Cephalosporine, Quinolone 66.7-76.9%, Carbapenem 29.7-35.9%. P. aeruginosa was
resistant to the tested antibiotics from 58.7 to 77.5%. The study results showed that the isolated bacteria were resistant to many commonly used antibiotics to varying degrees. Carbapenem-resistant gram-negative bacteria appeared at a high rate.