An optimised procedure for histological assessment of cartilage damage

Authors

  • Van Huy Dang
  • The Hoang Nguyen
  • Thi Minh Hanh Ngo, Thi Ngoc Anh Nguyen
  • Cong Nguyen Pham, Hai Anh Nguyen, Huu Phuong Anh Le
  • Duc Luong Nguyen
  • Kim Anh Nguyen, Ngoc Mai Nguyen
  • Huy Hoang Dao
  • Huu Giap Nguyen
  • Thu Huong Ngo, Van Ha Truong
  • Thi Huyen Trang Tran*

Keywords:

cartilage damage, repaired cartilage, Safranin O

Abstract

function if it is not detected and treated in time. Due to the avascular and nerveless nature of cartilage tissue, fully repairing hyaline cartilage remains a challenge for researchers. Besides, assessing the severity of damage and the effectiveness of treatment for cartilage damage is very important. Although various non-invasive longitudinal monitoring methods, such as ultrasound and magnetic resonance imaging, histopathology remains the “gold standard” for assessing joint cartilage quality. However, research on cartilage histopathology in Vietnam is still not yet widely conducted. This research aims to establish an efficient, feasible, and reliable evaluation process for cartilage histopathology in humans and experimental animals.

DOI:

https://doi.org/10.31276/VJST.2024.0008

Classification number

3.2

Author Biographies

Van Huy Dang

Department of Traumatology and Orthopaedics, 110 Military Hospital, 7 Tran Luu Street, Thi Cau Ward, Bac Ninh City, Bac Ninh Province, Vietnam

108 Insititute of Clinical Medicine and Pharmacy, 1 Tran Hung Dao Street, Bach Dang Ward, Hai Ba Trung District, Hanoi, Vietnam

The Hoang Nguyen

108 Insititute of Clinical Medicine and Pharmacy, 1 Tran Hung Dao Street, Bach Dang Ward, Hai Ba Trung District, Hanoi, Vietnam

Thi Minh Hanh Ngo, Thi Ngoc Anh Nguyen

Department of Pathology, 108 Military Central Hospital, 1 Tran Hung Dao Street, Bach Dang Ward, Hai Ba Trung District, Hanoi, Vietnam

Cong Nguyen Pham, Hai Anh Nguyen, Huu Phuong Anh Le

Center of Stem Cell Research and Application, 108 Military Central Hospital, 1 Tran Hung Dao Street, Bach Dang Ward, Hai Ba Trung District, Hanoi, Vietnam

The Vietnamese-German Center for Medical Research, 108 Military Central Hospital, 1 Tran Hung Dao Street, Bach Dang Ward, Hai Ba Trung District, Hanoi, Vietnam

Duc Luong Nguyen

Center of Stem Cell Research and Application, 108 Military Central Hospital, 1 Tran Hung Dao Street, Bach Dang Ward, Hai Ba Trung District, Hanoi, Vietnam

Kim Anh Nguyen, Ngoc Mai Nguyen

Center of Stem Cell Research and Application, 108 Military Central Hospital, 1 Tran Hung Dao Street, Bach Dang Ward, Hai Ba Trung District, Hanoi, Vietnam

The Vietnamese-German Center for Medical Research, 108 Military Central Hospital, 1 Tran Hung Dao Street, Bach Dang Ward, Hai Ba Trung District, Hanoi, Vietnam

Huy Hoang Dao

Center of Stem Cell Research and Application, 108 Military Central Hospital, 1 Tran Hung Dao Street, Bach Dang Ward, Hai Ba Trung District, Hanoi, Vietnam

Huu Giap Nguyen

Department of Diagnostic X-Ray, Department of Diagnostic Imaging, 108 Military Central Hospital, 1 Tran Hung Dao Street, Bach Dang Ward, Hai Ba Trung District, Hanoi, Vietnam

Thu Huong Ngo, Van Ha Truong

Department of Arthroplasty, 108 Military Central Hospital, 1 Tran Hung Dao Street, Bach Dang Ward, Hai Ba Trung District, Hanoi, Vietnam

Thi Huyen Trang Tran

Center of Stem Cell Research and Application, 108 Military Central Hospital, 1 Tran Hung Dao Street, Bach Dang Ward, Hai Ba Trung District, Hanoi, Vietnam

The Vietnamese-German Center for Medical Research, 108 Military Central Hospital, 1 Tran Hung Dao Street, Bach Dang Ward, Hai Ba Trung District, Hanoi, Vietnam

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Published

2025-03-25

Received 24 October 2023; revised 21 November 2023; accepted 23 November 2023

How to Cite

Dang Van Huy, Nguyen The Hoang, Ngo Thi Minh Hanh, Nguyen Thi Ngoc Anh, Pham Cong Nguyen, Nguyen Hai Anh, Le Huu Phuong Anh, Nguyen Duc Luong, Nguyen Kim Anh, Nguyen Ngoc Mai, Dao Huy Hoang, Nguyen Huu Giap, Ngo Thu Huong, Truong Van Ha, & Tran Thi Huyen Trang. (2025). An optimised procedure for histological assessment of cartilage damage. Version B of Vietnam Journal of Science and Technology, 67(3). https://doi.org/10.31276/VJST.2024.0008

Issue

Section

Medical and Pharmacological Sciences

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