Studying the humoral immune responses of rabbit to porcine circovirus type 2 (PCV2) isolated from pigs of Vietnam

Abstract

This study aimed to evaluate the immunogenicity of several isolates of porcine circovirus type 2 (PCV2) from pigs of Vietnam which are candidates for master seed selection. The experiments were done with 3 isolates having titer ≥ 105 TCID50/0.1 ml (namely isolate number 03, 04, and 07). All of immunized rabbits were able to produce specific antibodies against PCV2 which appeared around 14 days of post-immunization, and prolonged at least 56 days. Rabbits immunized by PCV2 of different passaging levels elicited humoral immune responses in similar manner as well as the viral neutralizing properties.