Assessment of clinical features and histopathologic type of non-Hodgkin lymphoma in head and neck

Abstract

Aims: to assess clinical features and histopathologic type of non-Hodgkin lymphoma in head and neck. Methods: retrospective and prospective studies on 98 patients with non-Hodgkin lymphoma in head and neck treatment with RCHOP. The study focused on describing the clinical and paraclinical symptoms of non-Hodgkin lymphoma.
Results: the group of age mostly acquired was 51-60 y.o.The proportion of male and female patients was 1/1.09. The time from symptoms begin to diagnose was mainly under 3 months. The most common non-Hodgkin lymphomas were located in tonsils 42.9%, neck node 34.7%, and arches 5.1% with symptoms such as otalgia, dysphagia, and neck node enlargement. Very rare lymphoma was found at eye socket 3.1%, nasal cavity 6.1%, and tongue base 8.2%. Cases with lymphadenopathy were estimated at 34.7%. Ann-Arbor stage II accounted for the largest part of 57.1%. Syndrome B was mainly stage II with 15.3%. In this research, the most common histopathology was diffuse large B-cell lymphoma (DLBCL) 70.4%, followed by mantle cell 8.18% and follicular lymphoma 7.14%. WF6 and WF7 were the most common histopathologic types. Conclusion: non-Hodgkin lymphoma in head and neck was mostly located in the Waldeyer’s ring with local symptoms of tumour, neck node enlargement; at the Ann-Arbor stage II, DLBCL was the most common histopathologic type.