Study on the ability to inhibit five cancer cell lines of the moringa root extract in in vitro conditions

Abstract

This study was conducted to evaluate the effect of moringa root extraction from seven different solvents and to evaluate the inhibition ability against five human cancer cell lines (breast cancer - MCF7, hepatic cancer - HepG2, lung cancer - SK-LU-1, blood cancer - Jurkat, and skin cancer - SK-Mel-2) in vitro. The results showed that the extraction efficiency of 7 different solvents was different, using the 96% ethanol solvent resulted in the highest extracting efficiency (19.66%). In addition, the root extraction using ethanol (96% ethanol) gave significantly higher levels of inhibitory effect on five human cancer cell lines than the root extraction using distilled water. At a concentration of 500 μg/ml, the root extracts with ethanol (96% ethanol) can inhibit and kill 96.38% of leukemia cells, 86.39% of breast cancer cells, 74.28% of skin cancer cells, 73.89% of lung cancer cells, and 66.22% of liver cancer cells.