The acute and chronic anti-inflammatory effects of Desmodium triquetrum extract

Abstract

The present study was conducted to evaluate the acute and chronic anti-inflammatory effects of the extracts from Desmodium triquetrum parts above the land surface on experimental animals. Desmodium triquetrum extracts at the doses of 4.8 gram and 14.4 gram per kilogram bodyweight of rats, and 9.6 gram and 28.8 gram per kilogram bodyweight of mice were used to study the acute and chronic anti-inflammatory effects. The ethylacetate segment and total extraction of Desmodium triquetrum at the doses of 4.8 and 14.4 g/ kg exhibited the acute anti-inflammatory effect through inhibiting carrageenan-induced edema in hind paw on rats. The ethylacetate segment of Desmodium triquetrum at the doses of 9.6 and 28.8 g/kg bodyweight of mice exhibited the chronic anti-inflammatory effect through the induction of peritoneal inflammation model.