Characterisation of marine-derived Streptomyces spp against pathogenic bacteria

Abstract

The aim of this study was to isolate and evaluate marine Streptomyces strains with an antibacterial activity against some pathogenic bacteria. From marine water and sediment samples collected from Hai Phong, Thanh Hoa, and Nghe An provinces, 35 Streptomyces strains were successfully isolated. Sixteen strains showed the antagonistic ability against Staphylococcus aureus ATCC 12222, Escherichia coli ATCC 25922, and Bacillus cereus ATCC 25923. Among them, ‘TH7’ strain had the highest antagonistic level. Morphological observation indicated that the colony of ‘TH7’ strain is round, dried, grey-white color with small particles in the center; substrate mycelia are brown; and aerial mycelia are linear, branched, but nonsegmented with a cicullar hook at the top of mycelium. This strain has the ability to produce extracellular enzymes as cellulase, amylase and protease, the salt tolerance up to 7%, and the good growth on the medium with different C resources and pH 5-9. In brief, this Streptomyces strain has the potential to produce not only extracellular enzymes but also antibacterial substances.